Avana 200 mg carries avanafil, a phosphodiesterase kind 5 inhibitor used to deal with erectile disorder (impotence) in men. at some point of sexual stimulation, nitric oxide is released into the erectile tissue of the penis, which turns on the enzyme guanylate cyclase. This enzyme increases the level of a chemical known as cyclic guanosine monophosphate (cGMP). This relaxes the blood vessels within the penis, permitting blood to fill the spongy erectile tissue and purpose an erection.