In Diablo 2 Resurrected, if the player wants to acquire Homunculus, then the player must kill a monster that drops it. This will only happen randomly. Although there is no guaranteed method of obtaining Homunclus in the game, there are some ways to increase the chance of obtaining Homunclus, that is, repeating the part of the D2 Resurrected Items game that is most likely to drop a monster.

The level of Homunculus is too high, and it is impossible to get it on normal difficulty. Players may get one in the palace cellar on Nightmare difficulty at the earliest, but don't expect it. The monster most likely to drop Homunculus is Baal on Nightmare difficulty, followed by Andariel on Hell difficulty, and then Mephisto on Hell difficulty.

All bosses of all bills on Hell difficulty, and all bosses of Chapter 3, Chapter 4, and Chapter 5 on Nightmare difficulty have a good chance to drop it. If the boss battle is too repetitive for the Diablo 2 Resurrected Items for Sale player, and the player would rather play the whole scene, then the fifth scene of Nightmare difficulty may be the player's best choice. This will almost certainly be a lot slower, but the player may be lucky.

In terms of pure physical defense, Homunculus is the best shield for necromancers, and it has a great improvement in all resistances. It is especially useful if the player uses a lot of curses, even though there are few recognized necromancers to build. In addition, if players have a great demand for the unique Diablo 2 Resurrected Items, then players can visit MMOWTS to purchase these D2R Items, and the prices they provide are the lowest.