Global Bioreactors Market size was valued at US$ XX Mn in 2019 and the total revenue is expected to grow at XX% through 2020 to 2026, reaching nearly US$ 12000 Mn.
The global Bioreactors Market report is a comprehensive analysis of the industry, market, and key players. The report has covered the market by demand and supply-side by segments. The global Bioreactors report also provides trends by market segments, technology, and investment with a competitive landscape.
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Global Bioreactors Market Overview:
A bioreactor is a device that provides a regulated environment that allows organisms like animal cells, mammalian cells, yeast cells, and bacteria to grow under controlled conditions. They're used in the manufacturing of pharmaceuticals like monoclonal antibodies and vaccines, among other things. The production of biological, biochemical, and biomechanically engineered products requires a regulated environment.
A bioreactor is a vessel, tub, or tank that acts as a biological catalyst to help biological raw materials undergo a chemical transformation. Bioreactors have been used to make high-value products and therapeutic biomolecules for a long time. Throughout the culture's ongoing reaction, these instruments regulate and track the environmental conditions.
An ideal bioreactor regulates and allocates a beneficial impact on the biological reaction, avoiding contamination from outside sources. When designing a bioreactor, operating costs and capital expenditure are important factors to consider.
Global Bioreactors Market Dynamics:
Drivers:
Large R&D investments increased adoption of single-use bioreactors, technological advances in bioreactors, and rapid growth of the pharmaceutical and biotechnology industries are driving the global bioreactors market.
Bioreactor innovations aid in the advancement of biological processes. Continuous manufacturing, process analytical technology, and single-use devices are among the innovations. For industrial biomanufacturing facilities, single-use bioreactors have been commonly used. They provide reduced contamination, multiple biologics output, and the ability to produce multiple goods on the same floor. Furthermore, favorable government legislation and manufacturing units that meet consumer needs can propel the industry forward.
The rising prevalence of chronic diseases such as cancer, cardiovascular disease, and diabetes would fuel the development of therapeutics, boosting the demand for bioreactors. The rise in personalized medicines, combined with the number of FDA-approved orphan drugs, has boosted bio development, accelerating demand for bioreactors in the coming years.
Restraints:
However, the global bioreactors market is hindered by the lack of availability and access to various alternative bioreactor methods, as well as an uncompromising regulatory environment for the system and materials used.
Regulatory concerns about the use of bioreactors, as well as increasingly strict government policy and regulation aimed at market growth, are limiting the market growth. Also, the market's growth is hampered by a lack of adequate storage facilities, susceptibility to leaching, and transportation. Furthermore, large-scale disposal of plastic derivatives is becoming an increasing environmental issue, limiting business expansion.
Global Bioreactors Market Segment Analysis:
Based on Type, the Continuous Stirred Tank Bioreactors segment dominated the Bioreactors Market in terms of revenue, in 2019 and is expected to expand at a CAGR of 5.91 percent, Owing to the increasing development of monoclonal antibodies (MAb) therapeutics and other biological using animal cell cultures. An impeller for homogenizing culture media and a sparger for supplying oxygen to the cells are included in the continuous stirred-tank reactors. It has a larger surface area for oxygen transfer, resulting in a higher product yield. These are primarily used in the manufacturing industry, inhomogeneous liquid-phase flow reactions requiring constant agitation, and in the pharmaceutical industry, contributing to the market's growth.
Based on Product, the reusable bioreactors market will account for more than 75% of total sales, owing to their increased use in bulk product manufacturing, 2020. Product demand is driven by high volume capacity and increased scalability. The use of single-use bioreactors in industrial manufacturing results in higher product costs due to repeated sales and installations. As a result, reusable systems would be preferred in these facilities. Furthermore, punctures are less likely in reusable bioreactors.
Based on Cell, the bioreactors market for mammalian cells will be worth USD 4 billion, in 2020. Bioreactor demand will be boosted by the widespread use of mammalian cells in the manufacture of therapeutic proteins and viral vaccines, among other biopharmaceuticals. Tissue analogs for regenerative medicines are generated using these cells. These cells' vulnerability and exposure to shear damage have provided significant growth opportunities for advanced bioreactors that use low agitation rates to achieve high throughput. As a result of the widespread use of mammalian cells in biopharmaceutical production, the segment is expected to expand rapidly in the future.
Based on Molecule, the vaccine segment accounted for over 47% of the bioreactors industry. Bioreactors will be in high demand due to extensive R&D activities for vaccine production. In recent years, the occurrence of serious infectious diseases has prompted vaccine development efforts.
COVID-19's emergence has prompted a surge in vaccine research and development around the world. For example, the Indian government announced the third stimulus package for COVID-19 vaccine production in November 2020.
Based on Usage, Developmental, pre-clinical & clinical segment in the bioreactors market is projected to grow significantly by 2026. The market for small-scale bioreactors have grown as the number of pre-clinical and clinical-stage studies in the production of various therapeutic drugs for rare and chronic diseases has increased. The bioreactors industry revenue is also boosted by pharmaceutical manufacturers' continued emphasis on product innovation and increased R&D expenditure.
Based on End-User, the biopharma manufacturers segment accounted for more than 40% of the bioreactors industry. In the coming years, the growing use of high-end technology to simplify complex manufacturing would boost demand for bioreactors. The use of bioreactors in the production and growth of complex molecules such as proteins and nucleic acids also boosts revenue in this segment.
Product adoption is favored by the need for bioreactors that support new, high-cell-density, and intensified processes that require high oxygen transfer and excellent carbon dioxide removal, thus propelling the segment value in the coming years.
Global Bioreactors Market Regional Insights:
Due to the obvious involvement of leading players focusing on product innovation, increasing R&D investment, and the rising prevalence of chronic diseases, the North American bioreactors market size was over USD 2 billion in 2020. Additionally, the region's growing number of academic institutes and expanding research and development facilities are driving up demand for bioreactors. Because of increasing public and private funding for R&D in this area, North America dominated the Bioreactors Market in terms of revenue in 2019, with a market share of 41.8 percent.
With the recent occurrence of COVID-19, the government support to fuel R&D for vaccine production has aided regional expansion. As a result, extensive research and development activities to develop novel biological drugs will drive growth in the coming years across the North American region.
In the United States, the National Institutes of Health (NIH) teamed up with 11 biopharmaceutical companies to form the "Partnership for Accelerating Cancer Therapies (PACT)" public-private research partnership. The collaboration's goal is to advance cancer immunotherapy, with a total investment of $215 million to help the market expand.
In 2019, Europe's bioreactor sector accounted for more than 37% of total sales. The consumer demand would be influenced positively by rising awareness, a wider patient pool suffering from chronic diseases, and increased healthcare spending potential. The involvement of existing players also has an effect on bioreactor availability and adoption in the area.
The objective of the report is to present a comprehensive analysis of the global Bioreactors Market to the stakeholders in the industry. The past and current status of the industry with the forecasted market size and trends are presented in the report with the analysis of complicated data in simple language. The report covers all the aspects of the industry with a dedicated study of key players that include market leaders, followers, and new entrants.
PORTER, SVOR, PESTEL analysis with the potential impact of micro-economic factors of the market have been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analyzed, which will give a clear futuristic view of the industry to the decision-makers.
The report also helps in understanding the global Bioreactors Market dynamics, structure by analyzing the market segments and project the global Bioreactors market size. Clear representation of competitive analysis of key players by product, price, financial position, product portfolio, growth strategies, and regional presence in the global Bioreactors Market make the report investor’s guide.
Global Bioreactors Market Key Developments:
Sartorius AG, a leading international biopharmaceutical partner, unveiled the ambr® 15 cell culture automated microbioreactor system in May 2019. For clone collection, media and feed optimization, and early process development work, it provides more versatility and capability.
QIAGEN, a leading supplier of life science and molecular diagnostic solutions, will be acquired by Thermo Fisher Scientific Inc. in March 2020. This acquisition enabled the company to take advantage of its industry-leading capabilities and R&D expertise to speed up innovation and meet evolving healthcare needs.
Danaher Corporation purchased the Biopharma business from General Electric Company's (NYSE: GE) Life Sciences division in March 2020. This acquisition aided the company is expanding across several categories and attracting a larger audience.
Eppendorf released SciVario twin, a bioreactor controller system for small bench-scale bioreactors, in February 2020. The introduction of a next-generation bio controller allowed for remote monitoring of cell culture processes, expanding the company's product line.
Global Bioreactors Market Scope: Inquire before buying
Global Bioreactors Market, by Type
• Continuous Stirred Tank Bioreactors
• Bubble Column Bioreactors
• Airlift Bioreactors
• Fluidized Bed Bioreactors
• Packed Bed Bioreactors
• Photo Bioreactors
Global Bioreactors Market, by Product
• Single-use
• Reusable
Global Bioreactors Market, by Cell
• Mammalian Cells
• Bacterial Cells
• Yeast Cells
• Others
Global Bioreactors Market, by Molecule
• Monoclonal Antibodies
• Vaccines
• Recombinant Proteins
• Stem Cells
• Gene Therapy
• Others
Global Bioreactors Market, by Usage
• Developmental, Pre-clinical & Clinical
• Commercial Production
Global Bioreactors Market, by End-User
• Research & Development Organization
• Biopharmaceutical Manufactures
• Contract Manufacturing Organizations (CMO)
Global Bioreactors Market, by Region
• North America
• Europe
• Asia Pacific
• The Middle East and Africa
• South America
Global Bioreactors Market Key Players
• Merck Group
• Cytiva
• Getinge (Applicon Biotechnology)
• Eppendorf AG
• Sartorius Group
• Thermo Fisher Scientific, Inc.
• GE Healthcare
• PBS Biotech
• TAP Biosystems
• Mani Dharma Biotech Pvt.Ltd
• Chemtrix
• CerCell
• Pall Corporation
• Other Key Players
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